The calculation for flow rate assumes turbulent flow. This is true for all normal heating circuits.
A warning is given if Laminar flow is likely. If in Laminar, the flow will be greater than shown. Look up flow using an on-line calculator.
Accuracy of this simulator is around 1-2% for most scenarios, but rises to almost 5% in more uncommon scenarios.
Elbow fittings and filters etc cause restriction. Don't forget to allow for this in your assessments.
There is a 15% flow reduction assumed for glycol. This is approximate.
Note, the outlet is always zero in our simulator since the outlet is open.